Preheat your oven to 350°F (175°C). Line a 9"x5" loaf pan with parchment paper or lightly grease it with butter.
In a medium bowl, whisk together 1 1/2 cups all-purpose flour, 1 teaspoon baking powder, and 1 teaspoon salt. Set aside.
In the bowl of an electric mixer (or using a hand whisk), blend together 1/3 cup melted unsalted butter, 1 cup granulated sugar, 2 eggs, 1/2 teaspoon vanilla extract, 2 teaspoons fresh grated lemon zest, and 2 tablespoons fresh lemon juice. Mix until well combined.
With the mixer on low speed, add the flour mixture and 1/2 cup milk in two batches (half the flour mixture, half the milk, then the rest of the flour and the rest of the milk). Mix just until combined—do not overmix.
If using fresh blueberries, rinse them so they have a bit of moisture. In a small bowl, toss 1 cup blueberries with 1 tablespoon flour to coat.
Gently fold the flour-coated blueberries into the batter by hand, just until evenly distributed.
Pour the batter into the prepared loaf pan and smooth the top. Bake for 55–65 minutes, or until a toothpick inserted in the center comes out clean. If the top browns too quickly, tent with foil during the last 10–15 minutes.
Let the bread cool in the pan for about 30 minutes, then transfer to a wire rack to cool completely.